DNA Repair of Cancer Stem Cells

• Corporate Author: SpringerLink (Online service)
• Other Authors: Mathews, Lesley A. (Editor), Cabarcas, Stephanie M. (Editor), Hurt, Elaine M. (Editor)
• Format: Electronic
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
• Subjects: Medicine.; Oncology.; Stem cells.; Biomedicine.; Biomedicine general.; Molecular Medicine.; Cancer Research.; Stem Cells.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-94-007-4590-2

The existence of cancer stem cells (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence.� CSCs are believed to be responsibl...

Table of Contents:

• Preface. -1 Introduction to Cancer stem cells.-2 DNA Repair Pathways and Mechanisms.-3 Resistance and DNA repair mechanisms of cancer stem cells: Potential molecular targets for therapy.-4 DNA Repair in Normal Stem Cells.-5 DNA Repair Mechanisms in Glioblastoma Cancer Stem Cells.-6 DNA Repair Mechanisms in Breast Cancer Stem Cells.7 DNA Repair Mechanisms in other Cancer Stem Cell models
• 8 Pancreatic cancer stem cells in tumor progression, metastasis, epithelial-mesenchymal transition and DNA repair.-9 Targeting Cancer Stem Cell Efficient DNA Repair Pathways: Screening for new therapeutics
• 10 The Future of DNA Repair and Cancer Stem Cells. Index.