Development of Novel Hydrogen-Bond Donor Catalysts

• Main Author: Inokuma, Tsubasa. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: Tokyo : Springer Japan : Imprint: Springer, 2013.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Chemistry.; Chemistry, Organic.; Biochemistry.; Catalysis.; Organic Chemistry.; Medicinal Chemistry.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-4-431-54231-5

This work describes novel, effective hydrogen-bond (HB) donor catalysts based on a known bifunctional tertiary amine-thiourea, a privileged structure, which has been proven to be one of the most widely used organocatalysts. These HB donor catalysts derived from quinazoline and benzothiadiazine were...

Table of Contents:

• Introduction
• Development of HB donor catalysts
• Development and properties of novel HB donor catalysts
• Asymmetric Michael addition to alpha,beta-unsaturated imides catalyzed by HB donors
• Asymmetric Hydrazination of activated methylene compounds catalyzed by HB donors
• Development of hydroxy thiourea catalysts
• Asymmetric Michael addition of gamma-hydroxyenones and alkenylboronic acids
• Asymmetric Petasis Reaction of N-aryl-alpha-iminoamides and Alkenylboronates
• Conclusion.