Molecular Mechanisms in Legionella Pathogenesis
Legionnaires<U+0019> disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on c...
| Corporate Author: | |
|---|---|
| Other Authors: | |
| Format: | Electronic |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2013.
|
| Series: | Current Topics in Microbiology and Immunology,
376 |
| Subjects: | |
| Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-642-40591-4 |
Table of Contents:
- From amoeba to macrophages: exploring the molecular mechanisms of Legionella infection in both hosts
- The Legionella pneumophila two-component regulatory systems that participate in the regulation of Icm/Dot effectors
- Facets of small RNA-mediated regulation in Legionella pneumophila
- Type II secretion and Legionella virulence
- Effector translocation by the Legionella Icm/Dot type IV secretion system
- Modulation of small GTPases by Legionella
- Host lipidation: A mechanism for spatial regulation of Legionella effectors
- Phosphoinositides and the Legionella pathogen vacuole
- Legionella phospholipases implicated in virulence
- Cytotoxic glucosyltransferases of Legionella pneumophila
- Modulation of the ubiquitination machinery by Legionella
- Host signal transduction and protein kinases implicated in Legionella infection
- Mouse models of Legionnairesþ disease.