Neurogenesis and Neural Plasticity

Neurogenesis and synaptogenesis, once thought to occur mainly during development, have now been established as key features of adult brain function.� Together they enable the brain to respond to both internal and external changes, giving the brain a previously unrecognised level of flexibility.� Alt...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Belzung, Catherine. (Editor), Wigmore, Peter. (Editor)
Format: Electronic
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
Series:Current Topics in Behavioral Neurosciences, 15
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-642-36232-3
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505 0 # |a Preface -- Part 1. Characterization -- Stem Cells. Hippocampal Neurogenesis. Olfactory Neurogenesis. Synaptogenesis. Neurotrophins -- Part 2. Environmental Factors -- Stress. Enrichment. Exercise. Cytotoxic Drugs and Memory -- Part 3. Diseases -- Depression. Addiction. Neurodegeneration -- Part 4. Ageing and Repair -- Ageing. Repair. 
520 # # |a Neurogenesis and synaptogenesis, once thought to occur mainly during development, have now been established as key features of adult brain function.� Together they enable the brain to respond to both internal and external changes, giving the brain a previously unrecognised level of flexibility.� Alterations in these two features can produce improvements in cognition but are also critically involved in the pathological responses of the brain seen in many psychiatric and neurological conditions.� This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain.� Ongoing neurogenesis and alterations in synapses are required for many functions of the brain including olfaction and hippocampal dependent memory.� Increased levels of synaptogenesis and neurogenesis are key aspects of the improved cognition seen after environmental enrichment and exercise.� However, changes in these features are also critical to the pathological response of the brain to stress, depression, neurodegeneration and cytotoxic drugs.� With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.�� 
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