CRISPR-Cas Systems RNA-mediated Adaptive Immunity in Bacteria and Archaea /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Barrangou, Rodolphe. (Editor), van der Oost, John. (Editor)
• Format: Electronic
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
• Subjects: Life sciences.; Microbiology.; Microbial genetics.; Life Sciences.; Microbial Genetics and Genomics.; Medical Microbiology.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-642-34657-6

CRISPR-Cas is a recently discovered defense system which protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR-Cas immune systems has been identified in at least half of the available prokaryotic genomes. On-going b...

Table of Contents:

• Discovery and seminal developments in the CRISPR field
• Occurrence, diversity of CRISPR-Cas systems and genotyping implications
• �Evolution and classification of CRISPR-Cas systems and Cas protein families
• Regulation of CRISPR-based immune responses
• crRNA Biogenesis
• Distribution and mechanism of the Type I CRISPR/Cas Systems
• Type II  Streptococcus thermophilus
• Type III CRISPR-Cas Systems and the Roles CRISPR-Cas in Bacterial Virulence
• CRISPR-Cas Systems to Probe Ecological Diversity and Host-Viral Interactions
• Roles of CRISPR in regulation of physiological processes
• Applications of the versatile CRISPR-Cas systems
• CRISPRs in microbial community context.