Prospects for Chemoprevention of Colorectal Neoplasia Emerging Role of Anti-Inflammatory Drugs /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Chan, Andrew T. (Editor), Detering, Elmar. (Editor)
• Format: Electronic
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
• Series: Recent Results in Cancer Research, 191
• Subjects: Medicine.; Internal medicine.; Cardiology.; Gastroenterology.; Oncology.; Colon (Anatomy) > Surgery.; Medicine & Public Health.; Internal Medicine.; Colorectal Surgery.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-642-30331-9

The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mech...

Table of Contents:

• What is chemoprevention today?- Mechanistic aspects in tumor development and progression of colorectal adenoma and carcinoma
• Mode of action of �aspirin as a chemopreventive agent
• Coxibs: pharmacology, toxicity and efficacy in cancer clinical trials
• COX-2 active agents in chemoprevention (includes aspirin, coxibs, and DFMO)
• New potential developments in aspirin/NSAID derivatives
• Aspirin in CRC chemoprevention in the context of other chronic diseases
• Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal adenoma and carcinoma
• Genetic risks for CRC and hereditary forms of CRC.  Strategies for prevention in high risk population.