Genomics of Pattern Recognition Receptors Applications in Oncology and Cardiovascular Diseases /

• Main Authors: Kutikhin, Anton G. (Author), Yuzhalin, Arseniy E. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: Basel : Springer Basel : Imprint: Springer, 2013.
• Subjects: Life sciences.; Oncology.; Human genetics.; Immunology.; Cardiology.; Cell receptors.; Life Sciences.; Receptors.; Cancer Research.; Human Genetics.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-0348-0688-6

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focu...

Table of Contents:

• The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation
• Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword
• Structural Genomic Variation in Toll-Like Receptor 4 and Cancer
• Structural Genomic Variation in Other Toll-like Receptors and Cancer
• Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer
• Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer
• Structural Genomic Variation in NOD-Like Receptors and Cancer
• Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases
• Hot Spots In the Field: Where Should We Go.