|
|
|
|
| LEADER |
03072nam a22005535i 4500 |
| 001 |
14177 |
| 003 |
DE-He213 |
| 005 |
20130727082358.0 |
| 007 |
cr nn 008mamaa |
| 008 |
130628s2013 sz | s |||| 0|eng d |
| 020 |
# |
# |
|a 9783034806794
|9 978-3-0348-0679-4
|
| 024 |
7 |
# |
|a 10.1007/978-3-0348-0679-4
|2 doi
|
| 050 |
# |
4 |
|a QH432
|
| 072 |
# |
7 |
|a PSVH
|2 bicssc
|
| 072 |
# |
7 |
|a PSAK1
|2 bicssc
|
| 072 |
# |
7 |
|a SCI070000
|2 bisacsh
|
| 072 |
# |
7 |
|a SCI29000
|2 bisacsh
|
| 082 |
0 |
4 |
|a 591.35
|2 23
|
| 100 |
1 |
# |
|a Barrett, Lucy W.
|e author.
|
| 245 |
1 |
0 |
|a Untranslated Gene Regions and Other Non-coding Elements
|b Regulation of Eukaryotic Gene Expression /
|c by Lucy W. Barrett, Sue Fletcher, Steve D. Wilton.
|h [electronic resource] :
|
| 264 |
# |
1 |
|a Basel :
|b Springer Basel :
|b Imprint: Springer,
|c 2013.
|
| 300 |
# |
# |
|a VIII, 56 p. 2 illus. in color.
|b online resource.
|
| 336 |
# |
# |
|a text
|b txt
|2 rdacontent
|
| 337 |
# |
# |
|a computer
|b c
|2 rdamedia
|
| 338 |
# |
# |
|a online resource
|b cr
|2 rdacarrier
|
| 347 |
# |
# |
|a text file
|b PDF
|2 rda
|
| 490 |
1 |
# |
|a SpringerBriefs in Biochemistry and Molecular Biology,
|x 2211-9353
|
| 505 |
0 |
# |
|a Introduction -- Promoter -- 5 Untranslated Region -- Structure -- Intronic Regions -- 3 Untranslated Region -- Non-coding RNAs -- Conclusion.
|
| 520 |
# |
# |
|a There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as junk DNA , it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5 and 3 untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
|
| 650 |
# |
0 |
|a Life sciences.
|
| 650 |
# |
0 |
|a Medical genetics.
|
| 650 |
# |
0 |
|a Nucleic acids.
|
| 650 |
# |
0 |
|a Plant breeding.
|
| 650 |
# |
0 |
|a Animal genetics.
|
| 650 |
1 |
4 |
|a Life Sciences.
|
| 650 |
2 |
4 |
|a Animal Genetics and Genomics.
|
| 650 |
2 |
4 |
|a Plant Genetics & Genomics.
|
| 650 |
2 |
4 |
|a Gene Function.
|
| 650 |
2 |
4 |
|a Nucleic Acid Chemistry.
|
| 700 |
1 |
# |
|a Fletcher, Sue.
|e author.
|
| 700 |
1 |
# |
|a Wilton, Steve D.
|e author.
|
| 710 |
2 |
# |
|a SpringerLink (Online service)
|
| 773 |
0 |
# |
|t Springer eBooks
|
| 776 |
0 |
8 |
|i Printed edition:
|z 9783034806787
|
| 830 |
# |
0 |
|a SpringerBriefs in Biochemistry and Molecular Biology,
|x 2211-9353
|
| 856 |
4 |
0 |
|u https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-0348-0679-4
|
| 912 |
# |
# |
|a ZDB-2-SBL
|
| 950 |
# |
# |
|a Biomedical and Life Sciences (Springer-11642)
|