Mesenchymal Stem Cell Therapy

• Corporate Author: SpringerLink (Online service)
• Other Authors: Chase, Lucas G. (Editor), Vemuri, Mohan C. (Editor)
• Format: Electronic
• Language: English
• Published: Totowa, NJ : Humana Press : Imprint: Humana Press, 2013.
• Series: Stem Cell Biology and Regenerative Medicine
• Subjects: Life sciences.; Cytology.; Stem cells.; Life Sciences.; Stem Cells.; Cell Biology.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-62703-200-1

 Mesenchymal Stem Cells or Multipotent Mesenchymal Stromal Cells (collectively referred to as MSCs) are currently being tested in a number of clinical trials for various diseases including graft-versus-host disease, Crohn s disease, myocardial infarction, stroke, diabetes, cartilage defects, and many others. The increasing number of clinical trials globally indicates the likely therapeutic potential of this specialized adult stem cell.� Over the last decade, there has been tremendous progress towards understanding an MSC s phenotype, expansion features in culture, differentiation ability and global gene and protein expression profiles.� Despite the enormous progress and data accrual at the molecular and cellular levels, several questions remain as to the utility of MSCs for clinical applications.� � Mesenchymal Stem Cell Therapy is a comprehensive collection of information comprised of both basic and pre-clinical biological studies as well as current advances in clinical applications within the MSC therapy field.� This text is a resource for both the basic life science and cell therapy researchers and includes a spectrum of review chapters from top experts in the field discussing clinical scale culture, regulatory issues, genetic engineering, disease specific applications and others.