Molecular Biology of Long Non-coding RNAs

• Corporate Author: SpringerLink (Online service)
• Other Authors: Khalil, Ahmad M. (Editor), Coller, Jeff. (Editor)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2013.
• Subjects: Medicine.; Human genetics.; Biochemistry.; Biomedicine.; Human Genetics.; Biomedicine general.; Protein Science.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-8621-3

Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity.�So, while their function is not entirely clear, they may ser...

Table of Contents:

• Preface
• Chromatin regulation by long non-coding RNAs
• Regulation of Eukaryotic Cell Differentiation by Long Noncoding RNAs
• Roles of long non-coding RNAs in X-chromosome inactivation
• Roles of Long Non-Coding RNAs in Genomic Imprinting
• Dysregulation of long noncoding RNAs in human disease
• Functions of long non-coding RNAs in non-mammalian systems
• Emerging technologies to study long non-coding RNAs
• Long non coding RNAs and nuclear body formation and function
• Index.