Gadd45 Stress Sensor Genes

• Corporate Author: SpringerLink (Online service)
• Other Authors: Liebermann, Dan A. (Editor), Hoffman, Barbara. (Editor)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2013.
• Series: Advances in Experimental Medicine and Biology, 793
• Subjects: Medicine.; Human genetics.; Medical genetics.; Biochemistry.; Biomedicine.; Gene Function.; Biochemistry, general.; Human Genetics.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-8289-5

Emerging evidence indicates that the Gadd45 family of genes play a unique and critical role as sensors of stress, including genotoxic, physiological and oncogenic stress. � The stress response Gadd45 family of genes (Gadd45a, Gadd45b & Gadd45g), discovered by Dr. Liebermann and other researchers...

Table of Contents:

• Gadd45 in stress signaling, cell cycle control and apoptosis
• Gadd45 in Modulation of Solid Tumors and Leukemia
• Gadd45 Proteins: Key players of repair-mediated DNA demethylation
• Gadd45 proteins in Immunity
• Gadd45 in the liver  Signal transduction and transcriptional mechanisms
• The Role of the Gadd45 Family in the Nervous System: A focus on Neurodevelopment, Neuronal Injury, and Cognitive Neuroepigenetics
• Gadd45 stress sensors in preeclampsia
• Index.