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Multiple Sclerosis Immunology A Foundation for Current and Future Treatments /

The availability of powerful genome-wide association study technology, during the last five years, has shown that most of the new MS susceptibility loci are immune-response genes. It is clear that there is much novelty in the field of MS immunology, which has served as an impetus to invest in new...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Yamamura, Takashi. (Editor), Gran, Bruno. (Editor)
Format: Electronic
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2013.
Subjects:
Medicine.
Medical genetics.
Immunology.
Biomedicine.
Gene Function.
Molecular Medicine.
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-7953-6
Table of Contents:
  • Th17 cells in autoimmune inflammation and demyelination in the central nervous system
  • Regulatory T cells in MS
  • T-bet: A critical regulator of encephalitogenic T Cells
  • Antigen-presenting cells in the Central Nervous System
  • The role of B cells in multiple sclerosis
  • Diet, gut flora and multiple sclerosis: current research and future perspectives
  • GM-CSF in autoimmune inflammation of the central nervous system
  • The role of Toll-like receptors in multiple sclerosis and experimental autoimmune encephalomyelitis
  • Macrophages and microglia in experimental autoimmune encephalomyelitis and multiple sclerosis
  • Genetics of multiple sclerosis
  • Gene expression profiling and pathway analysis for identification of molecular targets in MS
  • Systems biology for the study of multiple sclerosis
  • Checkpoints in the development of pathogenic and regulatory T cells in Experimental Autoimmune Encephalomyelitisa basis for current future interventions in MS
  • Modeling MS in non-human primates
  • A novel concept of treatment in MS: targeting both oligodendrocyte death and inflammatory processes by inhibiting poly (ADP-Ribose) polymerase
  • Association of MS with other autoimmune diseases
  • Current and future treatments of Multiple Sclerosis
  • Targeting CD52 for the treatment of Multiple Sclerosis
  • Haematopoietic stem cells for the treatment of MS
  • Mesenchymal stem cells for the treatment of Multiple Sclerosis.

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