Cholesterol and Presynaptic Glutamate Transport in the Brain
Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of�neurological and neurodegenerative disorders.� Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while�unbalanced lev...
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| Format: | Electronic |
| Language: | English |
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New York, NY :
Springer New York : Imprint: Springer,
2013.
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| Series: | SpringerBriefs in Neuroscience,
12 |
| Subjects: | |
| Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-7759-4 |
Table of Contents:
- Presynaptic glutamate transport in the brain
- Cholesterol and its role in synaptic transmission
- Effects of cholesterol-depleting agent methyl-b-cyclodextrin (MbCD) on the functional state of brain nerve terminals
- The extracellular level and uptake of glutamate in cholesterol-deficient nerve terminals
- Unstimulated and exocytotic glutamate release from cholesterol-deficient nerve terminals
- Neuroprotection by lowering cholesterol.