Immuno Systems Biology A macroscopic approach for immune cell signaling /

• Main Author: Selvarajoo, Kumar. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2013.
• Series: Systems Biology, 3
• Subjects: Medicine.; Immunology.; Bioinformatics.; Biological models.; Cytology.; Biomedicine.; Biomedicine general.; Systems Biology.; Computational Biology/Bioinformatics.; Cell Biology.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-7690-0

Technological advances of modern biology have generated high volumes of omics data. The natural precedence has been to put the complex information together, so that it will lead to spectacular scientific discoveries and medical breakthroughs. In this light, tremendous efforts worldwide are reshapi...

Table of Contents:

• Preface
• Systems biology of population cell response
• Perturbation-response approach for biological network analysis
• Basics of the mammalian immune system
• Inferring novel features of the TLR4 pathways
• Signaling Flux Redistribution
• Investigating the TLR3 signaling dynamics
• Understanding TNFR1 signaling dynamics
• TRAIL signaling in cancer
• Stochasticity and variability: insights from single cell dynamics
• Investigating single cell stochasticity in TRAIL signaling
• The distinction between single cell and population dynamics
• Finding chaos in biology
• Concluding remarks
• Index.