Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy Targeted Therapies to Reverse Resistance /

Patients with various cancers are treated with conventional chemotherapeutic drugs and the majority responds well to such therapies. However, there is a subset of patients who does not respond initially and another subset who no longer responds to further treatments. Clearly, in those two subsets of...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Bonavida, Benjamin. (Editor)
Format: Electronic
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2013.
Series:Resistance to Targeted Anti-Cancer Therapeutics, 1
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-7070-0
Table of Contents:
  • Preface
  • Multidrug resistance in cancer: a tale of ABC drug transporters
  • Multidrug resistance: a role for membrane physics, pH and drug transporters
  • Mechanisms and potential therapies for acquired resistance to inhibitors targeting the Raf or MEK kinases in cancer
  • Mechanisms of resistance to targeted B-Raf therapies
  • Role of ø1integrins in the complication and drug resistance against lung cancer: targeting ø1integrins to eradicate lung cancer
  • Aldo-keto reductases as new therapeutic targets for colon cancer chemoresistance
  • Overcoming drug resistance through elevation of ROS in cancer
  • Cancer stem cells in resistance to cytotoxic drugs: implications in chemotherapy
  • Two birds with a stone: molecular cancer therapy targeting signal transduction and DNA repair pathways
  • Collateral sensitivity in drug-resistant tumor cells
  • Human cancer resistance to trail-apoptotic pathway-targeted therapies
  • The dark side of apoptosis
  • Index.