Stem Cells and Prostate Cancer

• Corporate Author: SpringerLink (Online service)
• Other Authors: Cramer, Scott D. (Editor)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2013.
• Subjects: Medicine.; Oncology.; Cytology.; Biomedicine.; Cancer Research.; Cell Biology.; Biomedicine general.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-6498-3

Recent evidence demonstrates that normal prostate tissue contains stem cells.��There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells.��Both the normal prostate stem cell...

Table of Contents:

• Preface
• Stem Cells and Prostate Development
• Isolation and Characterization of Prostate Stem Cells
• Prostate tumor initiating cells
• TIC Markers and methods of characterization
• Genetic Control of Self Renewal of the TIC
• Therapeutic targeting of the prostate TIC.-�The prostate stem cell niche.-�Tumor stroma control of the prostate TIC.-�Targeting the prostate stem cell for chemoprevention.-�Stem cell models for functional validation of prostate cancer genes
• Index .