Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines
Development of new-generation vaccines is now more challenging than ever, as identifying, purifying and evaluating vaccine antigens is a complex undertaking. Most importantly, once the relevant antigens have been identified, key focus then shifts to the development of suitable delivery systems and f...
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Format: | Electronic |
Language: | English |
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Boston, MA :
Springer US : Imprint: Springer,
2013.
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Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-5380-2 |
Table of Contents:
- Critical parameters that govern the optimization of vaccine formulations
- Development of Biophysical assays to better understand vaccine formulation stability
- Rational design of vaccine formulations
- Monitoring stability and efficacy of multi-valent vaccine formulations.-��Overcoming challenges of multi component alum formulations.-��Delivery of various TLR adjuvants using alum platform
- History of use of emulsions for vaccine delivery
- MF59 o/w emulsion : History and safety over the last 2 decades
- Optimizing novel nanoemulsions for delivery of next generation antigens and adjuvants
- Modulating vaccine responses with innate immunity : Use of PLGA nanoparticles for delivering multiple TLR agonists
- Shape matters : Role of nanoparticle shape in induction of immune responses to a vaccine. � � � �.