Biophysical approaches to translational control of gene expression

• Corporate Author: SpringerLink (Online service)
• Other Authors: Dinman, Jonathan D. (Editor)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2013.
• Series: Biophysics for the Life Sciences ; 1
• Subjects: Medicine.; Gene expression.; Biochemistry.; Nucleic acids.; Crystallography.; Biomedicine.; Gene Expression.; Biophysics and Biological Physics.; Biochemistry, general.; Single Molecule Studies, Molecular Motors.; Nucleic Acid Chemistry.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-3991-2

When quantum mechanics was first proposed a century ago, nobody could have anticipated how deeply it would affect our lives.� Today, we are connected and powered through devices whose existence is predicated on the basic principles of this strange physics.� Not even the biological sciences have esca...

Table of Contents:

• X-ray analysis of prokaryotic and eukaryotic ribosomes
• A passage through the ribosome by Cryo-EM
• Molecular dynamics simulations of the ribosome
• Structural analyses of the ribosome by chemical modification methods
• Methods for studying the interactions of translation factors with the ribosome
• Riboproteomic approaches to understanding IRES elements
• Rapid kinetic analysis of protein synthesis
• Investigating RNAs Involved in Translational Control by NMR and SAXS
• Analyses of RNA-ligand interactions by fluorescence anisotropy
• Approaches for the Identification and Characterization of RNA-Protein Interactions
• A multidisciplinary approach to RNA Localization
• Virtual Screening for RNA-interacting Small Molecules
• The fifth RNA nucleotide: a role for ribosomal RNA pseudouridylation in control of gene expression at the translational level
• Translational Control of Synaptic Plasticity and Memory.