The Principles of Clinical Cytogenetics

• Corporate Author: SpringerLink (Online service)
• Other Authors: Gersen, Steven L. (Editor), Keagle, Martha B. (Editor)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2013.
• Edition: 3rd ed. 2013.
• Subjects: Medicine.; Human genetics.; Hematology.; Oncology.; Pathology.; Biomedicine.; Cytogenetics.; Human Genetics.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4419-1688-4

In this thoroughly revised and expanded third edition of the highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their descriptions of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurre...

Table of Contents:

• History of Clinical Cytogenetics
• DNA, Chromosomes, and Cell Division
• Human Chromosome Nomenclature: An Overview and Definition of Terms
• Basic Cytogenetics Laboratory Procedures
• The Essentials of Light Microscopy
• Quality Control & Quality Assurance
• Instrumentation in the Cytogenetics Laboratory
• Autosomal Aneuploidy
• Structural Chromosome Rearrangements
• Sex Chromosomes, Sex Chromosome Disorders, and Disorders of Sex Development
• The Cytogenetics of Infertility
• Prenatal Cytogenetics
• The Cytogenetics of Spontaneous Abortion
• Chromosome Instability
• The Cytogenetics of Hematologic Neoplasms
• The Cytogenetics of Solid Tumors
• Fluorescence in situ Hybridization (FISH)
• Microarray-Based Cytogenetics
• Fragile X: A Family of Disorders: Changing Phenotype and Molecular Genetics
• Genomic Imprinting and Uniparental Disomy
• Genetic Counseling.