Signal Transduction in Cancer Metastasis

The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published,...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Wu, Wen-Sheng. (Editor), Hu, Chi-Tan. (Editor)
Format: Electronic
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2010.
Series:Cancer Metastasis - Biology and Treatment, 15
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-90-481-9522-0
Table of Contents:
  • Preface
  • Chapter 1 Overview of signal transduction in tumor metastasis
  • Chapter 2 Multiple signal pathway triggering initiation of tumor metastasis
  • Chapter 3 Insights into the dynamics of focal adhesion protein trafficking in invasive cancer cells and clinical implications
  • Chapter 4 Grb2 and other adaptor proteins in tumor metastasis
  • Chapter 5 ERK1/2 MAP Kinase Signaling in Tumor Invasion and Metastasis
  • Chapter 6 MITOGEN-ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASES AND METASTASIS
  • Chapter 7 The signaling mechanism of ROS in tumor progression
  • Chapter 8 Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species
  • Chapter 9 Notch signaling and cancer metastasis
  • Chapter 10 New concepts on the critical functions of cancer- and metastasis-initiating cells in treatment resistance and disease relapse: Molecular mechanisms, signaling transduction elements and novel targeting therapies
  • Chapter 11 Involvement of lipid rafts in Growth factor receptors-mediated signaling for cancer metastasis
  • Chapter 12 Signal Transduction Pathways involved in Metastatic Liver Cancer
  • Chapter 13 Cadherins and signaling in ovarian cancer progression
  • Chapter 14 PTP4A3, a signal molecule deregulated in Uveal melanoma metastasis.