Endotoxins: Structure, Function and Recognition

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis,...

Full description

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Wang, Xiaoyuan. (Editor), Quinn, Peter J. (Editor)
Format: Electronic
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2010.
Series:Subcellular Biochemistry, 53
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-90-481-9078-2
Table of Contents:
  • Contributors
  • Part I Structure and Properties of Endotoxins
  • 1 Endotoxins: Lipopolysaccharides of Gram-negative Bacteria
  • 2 Purification and Characterization of Lipopoolysaccharides
  • 3 Endotoxins: Relationship between structure, function, and activity
  • 4 The diversity of the core oligosaccharide in lipopolysaccharides
  • 5 Salmonella-Regulated Lipopolysaccharide Modifications
  • 6 The variation of O antigens in Gram-negative bacteria
  • 7 Regulators of TLR4 signaling by endotoxins
  • 8 Membrane partitioning: is location everything when it comes to endotoxin recognition?
  • Part II Infection, Treatment and Immunity
  • 9 Endotoxin detection  from Limulus amebocyte lysate to recombinant Factor C
  • 10 The role of endotoxin in infection: Helicobacter pylori and Campylobacter jejuni
  • 11 The role of Pseudomonas lipopolysaccharide in cystic fibrosis airway infection
  • 12 Development of Small-molecule Endotoxin Sequestering Agents
  • 13 Development of an anti-endotoxin vaccine for sepsis
  • 14 Synthetic and Natural TLR4 Agonists as Safe and Effective Vaccine Adjuvants
  • 15 Targeting Endotoxin in the Treatment of Sepsis
  • 16 Lipopolysaccharides in Rhizobium-legume symbioses
  • 17 Lipopolysaccharides and plant innate immunity
  • Index.