The Challenge of Highly Pathogenic Microorganisms Mechanisms of Virulence and Novel Medical Countermeasures /
This book addresses the unique features of four microorganisms that constitute the top bioterror threat agents: Bacillus anthracis; Yersinia pestis, Francisella tularensis and Orthopoxviruses. Side-by-side updated information about their pathogenisis, virulence and epidemiology is provided in a sing...
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| Other Authors: | , , |
| Format: | Electronic |
| Language: | English |
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Dordrecht :
Springer Netherlands : Imprint: Springer,
2010.
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| Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-90-481-9054-6 |
Table of Contents:
- 1.The Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics
- 2. Proteomic Studies of Bacillus anthracis Reveal in vitro CO2-Modulation and Expression during Infection of Extracellular Proteases
- 3. Dynamics of Bacillus anthracis Infection and Control Mechanisms
- 4. Survival and Trafficking of Yersinia pestis in Non-Acidified Phagosomes in Murine Macrophages
- 5. The Inverse Relationship between Cytotoxicity of Y. pestis and its Virulence
- 6. The NlpD Lipoprotein of Yersinia pestis is Essential for Cell Separation and Virulence
- 7. Dissection of the Functions of the IglC Protein of Francisella tularensis
- 8. Yersinia pestis Lipopolysaccharide in Host-Pathogen Interactions
- 9. The Interactions between Pathogens and Dendritic Cells: From Paralysis of Cells to their Recruitment for Bacterial Colonization
- 10. Comparative Approaches to Identify Host Factors Specifically Targetted by Yersinia pestis during the Infectious Process
- 11. Poxvirus Entry into Host Cells
- 12. Role of A33R Amino-Acid 118L in the Interactions of Vaccinia Virus with the Host
- 13. Inhibitors of Innate Immunity from Vaccinia Virus
- 14. Brucella Species Synchronize their Life Cycle to the Gestation Cycle of their Ruminant Hosts
- 15. MMP-9 as a Marker for Vaccinia Virus Related Encephalitis
- 16. Epidemic Cowpoxvirus Infections in Germany
- 17. The Two Partner Secretion Transporters of Yersinia pestis: Cloning, Immunogenecity and in vivo Expression Following Airway Infection
- 18. Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX)
- 19. Subtyping Biothreat Bacterial Pathogens
- 20. A Rapid Method for Bacillus anthracis Genotyping
- 21. Tularemia <U+0013> A Disease with an Uncertain Impact on Public Health
- 22. Consequences of Antibiotic Treatment of Francisella tularensis Airways Infections
- 23. Novel Live Vaccine Candidates against Airborne Francisella tularensis
- 24. Effect of Disruption of mglA on the Virulence and Immunogenicity of the Francisella tularensis Live Vaccine Strain (LVS)
- 25. Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates
- 26. Modified Vaccinia Virus Ankara (MVA) based Vaccines <U+0013> Immunostimulatory and Protective Capacity
- 27. Therapeutic Potential of Vaccinia Hyper Immune Sera in Mouse Models of Lethal Orthopoxviruses Infection
- 28. A Live Plaque Vaccine Candidate with Improved Safety and Immunogenecity
- 29. Protection against Plague Afforded by Treatment with Polyclonal łLcrV and łF1 Antibodies
- 30. Combination of Anthrax-Toxin Neutralizing Antibodies: Analysis of Synergism/Antagonism Effect
- 31. The Efficacy of Antibiotic Treatment to Cure Guinea Pigs Intranasally Infected with Bacillus anthracis Spores
- 32. Reverse Vaccinology in Bacillus anthracis.